CSF Differential With Fewer Than 100 Cells: A Practical Reporting Guide
A cerebrospinal fluid (CSF) differential is ideally based on 100 identifiable nucleated cells—but low-cellularity specimens do not always provide that many. When the entire usable cytospin area contains fewer than 100 cells, the correct response is not to invent, duplicate, or “round up” cells. Count the cells that are actually present, document the denominator, and […]
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